CJC-1295 w/DAC 2mg
$34.99
Buy CJC-1295 with DAC at Wholesale Peptide
CJC-1295 with DAC is a big leap forward in growth hormone releasing hormone research applications, an extended half life compound for research on growth hormone secretion pathways. This synthetic peptide has gotten a lot of attention from the research community because of its drug affinity complex modification which research suggests may provide sustained biological activity in lab settings.
For researchers who want to buy cjc1295 with dac for their protocols, understanding the molecular characteristics, mechanism of action and handling requirements is essential for good research outcomes. The compound’s structural modifications and albumin binding properties make it very useful for studies that require prolonged growth hormone releasing effects.
Molecular Structure of CJC-1295 with DAC
CJC-1295 with DAC has a 30 amino acid sequence that is carefully designed to enhance stability and bioavailability in research applications. The full amino sequence is:
Amino Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-Lys(Mal)-NH2
The molecular specs show the compound’s complexity:
| Property | Value |
|---|---|
| Molecular Formula | C165H269N47O46 |
| Molecular Weight | 3367.954 g/mol |
| PubChem CID | 91976529 |
| CAS Number | 863288-34-0 |
The design incorporates several key modifications from natural ghrh. Research shows that 4 amino acid substitutions from the original releasing hormone ghrh sequence make it resistant to enzymatic breakdown. The most notable feature is the drug affinity complex modification at the C-terminus where a lysine linker (N-epsilon-3-maleimidopropionamide) allows albumin binding.
This lysine linker is a big innovation in peptide design. Research shows that the dac enhances the compound’s stability by binding to serum albumin which protects against degradation and extends the peptide’s half life significantly. The molecular structure has sequences like asp ala ile phe, ala ile phe thr, ile phe thr gln and gln asp ile leu that contribute to receptor binding affinity.
Mechanism of Action
CJC-1295 with DAC works by mimicking natural ghrh activity at the anterior pituitary gland level. Research shows this long acting analog binds to grf receptor sites on somatotropic cells and triggers growth hormone release cascades that affect multiple physiological pathways.
The mechanism involves several steps in experimental settings:
- Receptor Binding: The peptide attaches to growth hormone releasing hormone receptors on anterior pituitary cells
- Signal Transduction: Receptor activation triggers intracellular signaling pathways
- Growth Hormone Secretion: Stimulated cells increase growth hormone production and release
- Secondary Effects: Released growth hormone stimulates liver cells to produce insulin like growth factor
Research shows the drug affinity complex provides extended half life and more consistent growth hormone levels compared to natural ghrh. Studies show the peptide’s half life is around 6-8 days compared to 30 minutes for unmodified compounds. This extended duration may provide continuous stimulation rather than the pulsatile secretion pattern of shorter acting growth hormone releasing peptides.
The albumin binding mechanism allows for sustained release characteristics that research suggests can maintain elevated growth hormone levels for several days after a single injection in experimental models. This long lasting grf analog design may reduce administration frequency in research protocols while maintaining biological activity.
Research Studies
Scientific research on CJC-1295 with DAC has focused on pharmacokinetics, safety profiles and growth hormone releasing ability in experimental settings. Most research is preclinical with limited human studies in the published literature.
Animal model research shows this long acting analog increases plasma growth hormone and insulin like growth factor for extended periods. Studies have investigated:
- Pharmacokinetic Profiles: Research shows reduced administration frequency
- Growth Hormone Levels: Experimental data shows sustained elevation compared to natural ghrh
- Metabolic Parameters: Studies look at protein synthesis and metabolic function
- Safety Assessments: Preclinical research looks at adverse effects and tolerance
Research published in j clin endocrinol metab and similar publications has explored albumin binding peptides like CJC-1295 with DAC and noted their potential to create more stable systemic hormone levels. Studies suggest these compounds may be useful for research applications that require sustained growth hormone releasing effects.Research has been conducted on muscle growth, body composition and tissue repair. However long term safety data is limited and most research is in experimental settings under controlled laboratory conditions.
The ghrh knockout mouse model has provided valuable information on growth hormone releasing mechanisms but direct CJC-1295 with DAC studies in these models need to be done. Research shows the compound normalizes growth patterns and bone density and more research is warranted.
Storage and Safety
Proper storage and handling protocols are essential to maintain CJC-1295 with DAC stability and researcher safety in laboratory settings. The compound requires specific environmental conditions to preserve its molecular integrity and biological activity.
Storage Requirements
| Condition | Requirement |
|---|---|
| Lyophilized Form | -20°C or below for long term storage |
| Reconstituted Solution | 2-8°C refrigeration |
| Usage Timeframe | 2-3 weeks after reconstitution |
| Light Exposure | Protect from direct light |
Research shows peptides like CJC-1295 with DAC maintain optimal stability when stored according to these specifications. The lyophilized powder form provides extended shelf life when stored at proper temperatures, while reconstituted solutions require refrigeration and prompt usage.
Laboratory Safety Protocols
Researchers working with CJC-1295 with DAC must follow established laboratory safety procedures. The compound should only be handled by qualified personnel familiar with peptide handling protocols. Essential safety measures include:
- Proper personal protective equipment including gloves and laboratory attire
- Adequate ventilation in work areas
- Biosafety procedures appropriate for research chemical handling
- Proper waste disposal following institutional guidelines
Research shows that strict laboratory protocols ensure both compound integrity and researcher safety. The substance should be handled carefully to prevent contamination and maintain experimental validity.
Why Buy from Wholesale Peptide
Researchers looking to buy cjc1295 with dac for their research will find several benefits when purchasing from Wholesale Peptide. The vendor emphasizes quality assurance and research compliance throughout their operations.
Quality Assurance Standards
Wholesale Peptide implements strict quality control measures for all research compounds. Every batch is tested thoroughly using high-performance liquid chromatography (HPLC) to verify purity and molecular composition. This testing protocol ensures researchers receive compounds that meet their experimental requirements.
The third party testing approach provides independent verification of product specifications which research suggests is critical for experimental validity. HPLC analysis confirms the presence of the expected molecular structure and identifies potential impurities that can affect research outcomes.The vendor offers expedited shipping services to meet research timeline requirements. Same day shipping applies to orders placed before 1pm EST on business days, orders received after this time ship on the next business day. This shipping policy supports laboratories that need compound delivery fast for time sensitive experimental protocols.
Customer Support Policies
Wholesale Peptide has a 30 day money back guarantee on unopened products returned within the specified timeframe. This policy gives researchers peace of mind on product quality and helps with experimental planning.
The vendor is in compliance with research use only designations, all products carry the appropriate labeling and documentation. This supports researchers in meeting their institutional requirements.
Products from Wholesale Peptide are for Research Use Only
All products sold by Wholesale Peptide, including CJC-1295 with DAC, are research only. This means the product can only be used by qualified laboratory personnel for in-vitro studies and controlled experimental research.
The research use only designation has specific legal and regulatory implications that researchers must be aware of. The product cannot be used as a substance for human consumption, veterinary applications or any purpose outside of a controlled laboratory setting. Misbranding, mislabeling or misuse of these research products is strictly prohibited under applicable regulations.
This designation ensures researchers get products specifically designed for scientific research and comply with regulations governing research chemical distribution. It supports the scientific community’s need for high quality research products and prevents misuse.
Shipping Policy of Wholesale Peptide
Wholesale Peptide has efficient shipping procedures to support research timelines. Orders placed before 1pm EST Monday through Friday are processed and shipped same day. Orders received after 1pm EST or on weekends ship the following business day.
This shipping schedule accommodates research institutions that need predictable delivery times for experimental planning. The policy supports laboratories that manage multiple research projects with different compound requirements.
Satisfaction Guarantee
The vendor has a satisfaction guarantee on product quality and customer service. Researchers can return unopened products within 30 days for a full refund of the purchase price. This guarantee gives researchers confidence in product quality and helps with experimental planning.
The satisfaction guarantee reflects the vendor’s commitment to product quality and customer service in the research community. This policy allows researchers to buy products with confidence and control their experimental budgets.Every batch of CJC-1295 with DAC is tested by an independent third party using HPLC. This testing verifies product purity, confirms molecular composition and identifies any contaminants that could impact research results.
The third party testing gives objective verification of product specifications independent of vendor claims. Research shows independent testing is crucial for experimental validity and reproducibility across different research protocols.
HPLC analysis provides molecular characterization including purity percentages and impurity profiles. This information helps researchers evaluate compound suitability for their specific experimental requirements while maintaining quality standards.
Testing results are available upon request, for transparency on product specifications. This is helpful for researchers to document compound characteristics for publication and regulatory compliance purposes.
The testing protocol shows the vendor’s commitment to supporting high quality research through reliable compound sourcing. Independent verification ensures researchers get compounds that meet their experimental specifications and have confidence in their research results.
For researchers looking to buy cjc1295 with dac for their research, Wholesale Peptide offers a complete solution for product quality, regulatory compliance and customer service. The vendor’s emphasis on third party testing, proper labeling and research use only designation supports the scientific community’s need for reliable research products and regulatory compliance.
References
- Sackmann-Sala, L., Ding, J., Frohman, L. A., & Kopchick, J. J. (2009). Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects. Growth Hormone & IGF Research, 19(6), 471-477. https://doi.org/10.1016/j.ghir.2009.06.002
- Van Hout, M. C., & Hearne, E. (2016). Netnography of female use of the synthetic growth hormone CJC-1295: pulses and potions. Substance Use & Misuse, 51(1), 73-84. https://doi.org/10.3109/10826084.2015.1060244
- Alba, M., Fintini, D., Sagazio, A., Lawrence, B., Castaigne, J. P., Frohman, L. A., & Salvatori, R. (2006). Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse. American Journal of Physiology-Endocrinology and Metabolism, 291(6), E1290-E1294. https://doi.org/10.1152/ajpendo.00262.2006
- Knoop, A., Thomas, A., Fichant, E., Delahaut, P., Schänzer, W., & Thevis, M. (2016). HPLC-MS/MS analysis of growth hormone-releasing hormones in human plasma after immunoaffinity purification. Analytical and Bioanalytical Chemistry, 408, 3145-3153. https://doi.org/10.1007/s00216-016-9402-7
- Jette, L., et al. [CJC-1295 and GH]. Journal, Volume, Issue, pages. (Please add specific citation details)
- Kopchick, J. J., et al. [DAC technology]. Journal, Volume, pages. (Please add specific citation details)
For more information on CJC-1295 with DAC, consult Wikipedia.
| Weight | .001 lbs |
|---|
Related products
